Structured topics spanning clinical skills, core diseases, scoring systems, and transplant medicine. Each includes a clinical deep dive for when you're ready to go further.
The hepatology history has specific inflection points most standard curricula miss — alcohol quantification, herbal supplements, family history of liver disease.
Clinical SkillsSpider angiomata, palmar erythema, caput medusae, shifting dullness — the findings that tell a story before the labs come back.
Clinical SkillsConsent, site selection, Z-track technique, and the fluid studies that distinguish various etiologies of ascites.
Clinical SkillsCouinaud segments, hepatic vasculature, biliary anatomy, and surgical scissurae — the foundation for understanding imaging reports, resection planning, and transplant surgery.
AST, ALT, ALP, GGT, bilirubin — learn the patterns that distinguish hepatocellular from cholestatic injury and when to act on mild elevations.
Scoring SystemsFrom TIPS to MELD 3.0 — the full history, formula, and clinical application of the score that helps determine liver transplant prioritization.
InterpretationThe serum-ascites albumin gradient, SBP diagnosis and its variants, traumatic tap correction, and the evidence behind primary and secondary antibiotic prophylaxis.
InterpretationFIB-4, APRI, ELF, and FibroSure for serum-based staging — plus VCTE, shear wave elastography, and MRE. Includes the MASLD clinical decision pathway and Baveno VII criteria.
Portal hypertension, ascites, SBP, varices, HRS, hepatic encephalopathy, and HCC surveillance — with management principles at each stage.
Supportive CareSarcopenia is an independent predictor of mortality and waitlist dropout. Learn why nutrition is a therapeutic intervention, not an afterthought.
Core DiseaseFrom steatosis to alcohol-associated hepatitis to cirrhosis — MDF and Lille calculators, steroid dosing, MAT agents for AUD, and nutrition in severe AAH.
Core DiseaseAIH, PBC, and PSC — simplified diagnostic criteria, treatment options, and cancer surveillance in PSC.
Core DiseaseHFE mutations, iron overload screening, phlebotomy protocol, and why ferritin alone is insufficient — with organ-by-organ consequences of untreated iron excess.
Core DiseasePN-induced liver disease from steatosis to cirrhosis — risk factors, lipid emulsion selection, cyclic PN, and catheter care.
Core DiseaseFulminant hepatic failure from acetaminophen overdose, viral hepatitis, Wilson disease, and beyond — King's College Criteria, NAC protocol, and transplant indications.
Core DiseaseFunctional renal failure in advanced cirrhosis — RAAS/splanchnic vasodilation physiology, HRS-AKI vs HRS-CKD, terlipressin, and the albumin-in-SBP data that prevents it.
Core DiseaseThe 2023 nomenclature overhaul, MetALD, FIB-4 and FibroScan for fibrosis staging, and two newly FDA-approved therapies — resmetirom and semaglutide for MASLD F2–F3.
Core DiseaseATP7B mutations, the paradoxically low ALP in fulminant copper toxicity, Leipzig scoring, and why trientine has replaced D-penicillamine as first-line chelation therapy.
Core DiseaseBudd-Chiari syndrome and portal vein thrombosis — thrombophilia workup, stepwise management from anticoagulation through TIPS, and the tumor thrombus vs. bland thrombus distinction in HCC.
Acute liver failure, decompensated cirrhosis, HCC, oncologic exception pathways, and polycystic liver disease — how patients are listed and what moves them up the waitlist.
IntestinalShort gut syndrome, parenteral nutrition dependence, and the rare but critical indications for intestinal transplant.
Transplant MedicineRecipient hepatectomy, the anhepatic phase, graft implantation — and early complications including PNF, EAD, hepatic artery thrombosis, and biliary leaks.
Transplant MedicineCalcineurin inhibitors, antimetabolites, mTOR inhibitors, induction agents, rejection types, and the long-term complications that define post-LT survivorship.
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